The New Orleans Saints will have another chance to get back on track at home in Week 5, but oddsmakers expect a tight matchup against the Minnesota Vikings. New Orleans opened as a 1.5-point home underdog in a week highlighted by several significant line movements and a Monday night showdown between the Buffalo Bills and Los Angeles Rams.
The slate’s other premier matchup features the undefeated San Francisco 49ers heading to Seattle for an NFC West showdown against the defending Super Bowl champion Seahawks.
NFL Week 5 spread are subject to change. Here’s the direct link to those odds at BetOnline Sports & Casino : https://www.betonline.ag/sportsbook/football/nfl.
If there’s a line movement from the look-ahead lines, that will be notated. Some of the line movements were very noticeable including:
- Bears at Packers moved 3.5 points, from Packers -2.5 to +1.
- Broncos at Chargers moved 2 points, from Chargers +1.5 to +3.5.
NFL Week 5 Lines
Thursday, October 8, 2026
- Tampa Bay Buccaneers at Dallas Cowboys (-9.5)
Sunday, October 11, 2026
- Philadelphia Eagles vs Jacksonville Jaguars (-3.5)
- Lookahead line was Jaguars -3.
- Note: Game is in London.
- Chicago Bears at Green Bay Packers (+1)
- Lookahead line was Packers -2.5.
- Houston Texans at Tennessee Titans (+6.5)
- Cincinnati Bengals at Miami Dolphins (+7.5)
- Lookahead line was Dolphins +9.
- Las Vegas Raiders at New England Patriots (-4)
- Lookahead line was Patriots -3.5.
- Minnesota Vikings at New Orleans Saints (+1.5)
- Cleveland Browns at New York Jets (-1.5)
- Lookahead line was Jets -2.5
- Indianapolis Colts at Pittsburgh Steelers (-1.5)
- Lookahead line was Steelers -2.5
- New York Giants at Washington Commanders
- Lookahead line was Commanders -2.5.
- Line is currently off the board due to uncertainty at QB for Commanders.
- Denver Broncos at Los Angeles Chargers (+3.5)
- Lookahead line was Chargers +1.5.
- Detroit Lions at Arizona Cardinals (+5.5)
- Lookahead line was Cardinals +5.
- San Francisco 49ers at Seattle Seahawks (-3)
- Baltimore Ravens at Atlanta Falcons
- Lookahead line was Falcons +6.
- Line is currently off the board due to Lamar Jackson uncertainty.
Monday, October 12, 2026
- Buffalo Bills at Los Angeles Rams (-2.5)
