Jun 8, 2025; Pittsburgh, Pennsylvania, USA; Pittsburgh Pirates starting pitcher Paul Skenes (30) pitches against the Philadelphia Phillies during the fourth inning at PNC Park. Mandatory Credit: Charles LeClaire-Imagn Images
By Matt Moscona
Paul Skenes was the National Player of the Year and a national champion at LSU in 2023. Jacob Misiorowski signed with the Tigers, but never made it to campus after the Milwaukee Brewers selected him 63rd overall in the 2022 MLB Draft.
Skenes and Misiorowski could have been teammates with the Tigers in 2023. On Wednesday, the pair will face off against each other as the Brewers host the Pirates.
The oddsmakers at BetOnline.ag have created some intriguing props for this pitching duel.
Last year, Skenes started the All-Star Game and was Rookie of the Year. This year, Skenes is an overwhelming favorite to win Cy Young while Misiorowski, after only two starts, is the new Rookie of the Year favorite.
Skenes/Misiorowski props: https://www.betonline.ag/sportsbook/futures-and-props/mlb-specials/skenes-vs-misiorowski
Cy Young odds: https://www.betonline.ag/sportsbook/futures-and-props/mlb-player-futures/cy-young-winners
Rookie of the Year odds: https://www.betonline.ag/sportsbook/futures-and-props/mlb-player-futures/rookie-of-the-year
Skenes vs Misiorowski
Game Line 6/25/25
Pittsburgh Pirates -134
Milwaukee Brewers +122
Over/Under 7 runs
Paul Skenes hits allowed
Over/Under 3.5
Paul Skenes runs allowed
Over/Under 1.5
Paul Skenes strikeouts
Over/Under 7.5
Paul Skenes pitches 100+ MPH
Over/Under 2.5
Note: In his last three starts, Skenes has thrown 1 pitch at 100 mph, 14 at 99 mph and 48 at 98 mph. Oddsmakers must suspect adrenaline will kick in.
Jacob Misiorowski hits allowed
Over/Under 3
Note: He has allowed one hit in 11 innings pitched thus far.
Jacob Misiorowski runs allowed
Over/Under 1.5
Jacob Misiorowski strikeouts
Over/Under 5.5
Jacob Misiorowski pitches 100+ MPH
Over/Under 21.5
Note: In two starts, Misiorowski has thrown 3 pitches at 102 mph, 15 at 101 mph and 25 at 100 mph.
Who will hit a batter first?
Paul Skenes +100 (1/1)
Jacob Misiorowski -140 (5/7)
Awards Lines
| 2025 NL Cy Young | ||
| Paul Skenes | 1/5 | (-500) |
| Zack Wheeler | 8/1 | |
| Logan Webb | 11/1 | |
| Yoshinobu Yamamoto | 25/1 | |
| Mackenzie Gore | 28/1 | |
| Chris Sale | 40/1 | |
| Cristopher Sanchez | 45/1 | |
| Robbie Ray | 45/1 | |
| Jesus Luzardo | 50/1 | |
| Spencer Schwellenbach | 50/1 | |
| Freddy Peralta | 66/1 | |
| Sonny Gray | 80/1 | |
| Clay Holmes | 100/1 | |
| Hunter Greene | 100/1 | |
| 2025 NL Rookie of the Year | ||
| Jacob Misiorowski | 3/2 | (+150) |
| Drake Baldwin | 5/2 | (+250) |
| Agustin Ramirez | 6/1 | |
| Chase Burns | 14/1 | |
| Hyeseong Kim | 18/1 | |
| Ben Casparius | 25/1 | |
| Matt Shaw | 25/1 | |
| Ronny Mauricio | 25/1 | |
| Bubba Chandler | 28/1 | |
| Cade Horton | 28/1 | |
| Chad Patrick | 28/1 | |
| Dylan Crews | 28/1 | |
| Logan Henderson | 28/1 | |
| Mick Abel | 33/1 | |
| Brady House | 50/1 | |
| Dalton Rushing | 50/1 | |
| Luisangel Acuna | 50/1 | |
| Robert Hassell Ill | 50/1 | |
| Jordan Lawlar | 55/1 | |
| Liam Hicks | 60/1 | |
| Caleb Durbin | 66/1 | |
| Andrew Painter | 100/1 | |
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