Vanderbilt opens as small favorite over LSU

By Matt Moscona

Week 8 is highlighted by two huge SEC matchups with Ole Miss headed to Athens to face Georgia and Tennessee visiting Tuscaloosa to take on Alabama.

Penn State is an underdog this week so they can’t lose a third game in a row when favored by more than 20 points.

Below are the opening lines for Week 8, courtesy of BetOnline.ag.

Week 8 College Football Lines

Tuesday, October 14, 2025

• New Mexico State at Liberty (-10.5)

• Arkansas State at South Alabama (-7.5)

• Florida International at Western Kentucky (-8)

Wednesday, October 15, 2025

• Delaware at Jacksonville State (+1.5)

• UTEP at Sam Houston (+2.5)

Thursday, October 16, 2025

• Tulsa at East Carolina (-16.5)

Friday, October 17, 2025

• Louisville at Miami (-13)

• Nebraska at Minnesota (+6)

• San José State at Utah State (-4)

• North Carolina at California (-10.5)

Saturday, October 18, 2025

• Oklahoma at South Carolina (+5)

• LSU at Vanderbilt (-1.5)

• Missouri at Auburn (-1.5)

• Florida Atlantic at South Florida (-21)

• Texas at Kentucky (+12)

• UTSA at North Texas (-5.5)

• Georgia Tech at Duke (-2.5)

• Washington at Michigan (-6.5)

• UConn at Boston College (-1.5)

• Arizona at Houston (-2.5)

• Baylor at TCU (-3)

• Army at Tulane (-10.5)

• Central Michigan at Bowling Green (-6)

• Eastern Michigan at Miami (OH) (-11.5)

• West Virginia at UCF (-7)

• Kent State at Toledo (-24.5)

• Buffalo at Massachusetts (+17)

• Purdue at Northwestern (-3)

• Troy at UL Monroe (+5.5)

• Ohio State at Wisconsin (26.5)

• Ole Miss at Georgia (-6.5)

• Texas A&M at Arkansas (+7.5)

• Michigan State at Indiana (-26.5)

• SMU at Clemson (-10)

• Wyoming at Air Force (-5)

• UNLV at Boise State (-10.5)

• Coastal Carolina at Appalachian State (-11.5)

• Old Dominion at James Madison (-2)

• Texas State at Marshall (+3.5)

• Temple at Charlotte (+10.5)

• Akron at Ball State (-1.5)

• Northern Illinois at Ohio (-12)

• Texas Tech at Arizona State (+11)

• Memphis at UAB (+21)

• Mississippi State at Florida (-10)

• Southern Miss at Louisiana (+4)

• Oregon at Rutgers (+14.5)

• Washington State at Virginia (-18)

• Penn State at Iowa (-3)

• Maryland at UCLA (-2.5)

• Hawai’i (pk) at Colorado State (pk)

• Georgia State at Georgia Southern (-6)

• Tennessee at Alabama (-8)

• USC at Notre Dame (-8.5)

• Pittsburgh at Syracuse (+11)

• Utah at BYU (+3.5)

• Cincinnati at Oklahoma State (+20.5)

• Nevada at New Mexico (-10.5)

• Florida State at Stanford (+17.5)