LSU-Alabama line drops? Tigers draw early action in Week 11

By Matt Moscona

The Week 11 slate in college football features Frank Wilson’s debut as LSU interim head coach when the Tigers head to Tuscaloosa to take on No. 4 Alabama. If the Tigers pull off the upset, they will have to do it as a double-digit underdog.

Alabama opens as a 10.5-point favorite over LSU.

Below are the opening lines for Week 11, courtesy of BetOnline.ag.

College football Week 11 lines are subject to change. Here’s the direct link to real-time spreads: https://www.betonline.ag/sportsbook/football/ncaa.

Week 11 College Football Lines

Tuesday, November 4, 2025

• Massachusetts at Akron (-10.5)

• Miami (OH) at Ohio (-3.5)

Wednesday, November 5, 2025

• Kent State at Ball State (-2.5)

• Northern Illinois at Toledo (-14)

Thursday, November 6, 2025

• Georgia Southern at Appalachian State (-6.5)

• UTSA at South Florida (-13.5)

Friday, November 7, 2025

• Houston at UCF (-1)

• Northwestern at USC (-15)

• Tulane at Memphis (-6.5)

Saturday, November 8, 2025

• Indiana at Penn State (+13.5)

• Oregon at Iowa (+5.5)

• Nebraska at UCLA (+2)

• Washington at Wisconsin (+10.5)

• Georgia at Mississippi State (+7.5)

• BYU at Texas Tech (-10.5)

• SMU at Boston College (+12)

• Colorado at West Virginia (-6)

• James Madison at Marshall (+13)

• Southern Miss at Arkansas State (+5.5)

• Temple at Army (-6.5)

• Ohio State at Purdue (+28.5)

• Missouri State at Liberty (-8)

• Bowling Green at Eastern Michigan (-1.5)

• UAB at Rice (-3.5)

• Maryland at Rutgers (-1)

• Louisiana Tech at Delaware (+4)

• Florida International at Middle Tennessee (+1)

• Jacksonville State at UTEP (+1)

• Charlotte at East Carolina (-28.5)

• Tulsa at Florida Atlantic (-4.5)

• Texas A&M at Missouri (+6.5)

• Duke at UConn (+8.5)

• Kansas at Arizona (-6.5)

• Iowa State at TCU (-6.5)

• Auburn at Vanderbilt (-7)

• Kennesaw State at New Mexico State (+6.5)

• Syracuse at Miami (-28)

• Georgia State at Coastal Carolina (-7.5)

• Stanford at North Carolina (-9)

• Texas State at Louisiana (+2.5)

• Air Force at San Jose State (-3.5)

• Wake Forest at Virginia (-6.5)

• California at Louisville (-18.5)

• Florida State at Clemson (-2)

• LSU at Alabama (-10.5)

• Navy at Notre Dame (-24.5)

• Florida at Kentucky (+3)

• Nevada at Utah State (-10.5)

• UNLV at Colorado State (+5.5)

• Sam Houston at Oregon State (-18.5)

• San Diego State at Hawai’i (+5)