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Week 13’s slate top game is an old Pac 12 battle between USC and Oregon.
Two top ten teams (Alabama and Texas A&M) are playing FCS programs this week.
Below are the opening lines for Week 13, courtesy of BetOnline.ag.
College football Week 13 lines are subject to change. Here’s the direct link to real-time spreads: https://www.betonline.ag/sportsbook/football/ncaa.
Week 12 Football Lines
Tuesday, November 18, 2025
- Akron at Bowling Green (-3½)
- Massachusetts at Ohio (-32)
- Western Michigan at Northern Illinois (+6)
Wednesday, November 19, 2025
- Miami (Ohio) at Buffalo (-1½)
- Central Michigan at Kent State (+8)
Thursday, November 20, 2025
- Louisiana at Arkansas State (-3)
Friday, November 21, 2025
- Florida State at NC State (+5)
- Hawai’i at UNLV (-2½)
Saturday, November 22, 2025
- Rutgers at Ohio State (-33½)
- USC at Oregon (-9½)
- Arkansas at Texas (-10)
- BYU at Cincinnati (+2)
- Kansas State at Utah (-16½)
- Miami at Virginia Tech (+16½)
- Pittsburgh at Georgia Tech (-3)
- Michigan at Maryland (+12)
- Louisville at SMU (-3½)
- Michigan State at Iowa (-17)
- Tennessee at Florida (+3½)
- South Florida at UAB (+21)
- Nebraska at Penn State (-10)
- Minnesota at Northwestern (-4)
- Washington at UCLA (+10½)
- Illinois at Wisconsin (+9)
- Washington State at James Madison (-13½)
- Duke at North Carolina (+6½)
- Baylor at Arizona (-6½)
- Arizona State at Colorado (+7½)
- TCU at Houston (-2)
- Kansas at Iowa State (-4½)
- Colorado State at Boise State (-17)
- San Jose State at San Diego State (-11½)
- East Carolina at UTSA (+3)
- North Texas at Rice (-17½)
- Tulane at Temple (+8½)
- Missouri at Oklahoma (-9½)
- Delaware at Wake Forest (-18)
- Tulsa at Army (-10½)
- Charlotte at Georgia (-45)
- Old Dominion at Georgia Southern (+10)
- Missouri State at Kennesaw State (-6½)
- Nevada at Wyoming (-7½)
- Ball State at Toledo (-26)
- Marshall at Appalachian State (+3)
- UConn at Florida Atlantic (+7)
- Liberty at Louisiana Tech (-1½)
- Sam Houston at Middle Tennessee (-6)
- New Mexico State at UTEP (-3)
- Syracuse at Notre Dame (-35)
- Kentucky at Vanderbilt (-9½)
- Jacksonville State at Florida International (-1)
- Southern Miss at South Alabama (+2)
- Oklahoma State at UCF (-14½)
- Georgia State at Troy (-12½)
- Coastal Carolina at South Carolina (-23)
- UL Monroe at Texas State (-18½)
- New Mexico (pk) at Air Force (pk)
- California at Stanford (+3)
- Western Kentucky at LSU (-21½)
- Utah State at Fresno State (-2½)

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