Saints open as home underdog vs. Panthers

By Matt Moscona

The New Orleans Saints upset the Buccaneers on the road Sunday, but that didn’t move the oddsmakers’ feeling about the Week 15 matchup against Carolina.

The Saints opened as a three-point underdog at home against the Panthers who were idle in Week 14. Tyler Shough earned his first career win as a starter earlier this year at Carolina.

NFL Week 15 spreads are subject to change. Here’s the direct link to those odds: https://www.betonline.ag/sportsbook/football/nfl.

NFL Week 15 Lines

Thursday, December 10, 2025

• Atlanta Falcons at Tampa Bay Buccaneers (-5½)

Sunday, December 14, 2025

• Cleveland Browns at Chicago Bears (-7)

• Baltimore Ravens at Cincinnati Bengals (+2½)

• Los Angeles Chargers at Kansas City Chiefs (-4½)

• Buffalo Bills at New England Patriots (+1½)
  • Note: Lookahead line opened Patriots -1½. We have a new favorite in this game.

• Washington Commanders at New York Giants (-1½)
  • Note: Lookahead line opened Giants +2½. We have a new favorite.

• Las Vegas Raiders at Philadelphia Eagles (-13)

• New York Jets at Jacksonville Jaguars (-11½)
  • Note: Lookahead line opened Jaguars -9½.

• Arizona Cardinals at Houston Texans (-7½)

• Green Bay Packers at Denver Broncos (+1½)
  • Note: Lookahead line opened as a pick’em.

• Detroit Lions at Los Angeles Rams (-4½)

• Carolina Panthers at New Orleans Saints (+3)

• Tennessee Titans at San Francisco 49ers (-12½)

• Indianapolis Colts at Seattle Seahawks (-10)
  • Note: Lookahead line opened Colts -3½. Injury to Jones moved this game 6½ points.

• Minnesota Vikings at Dallas Cowboys (-6)
  • Note: Lookahead line opened Cowboys -7

Monday, December 15, 2025

• Miami Dolphins at Pittsburgh Steelers (-3½)