If the Saints make a dramatic turnaround under first year head coach Kellen Moore, it will come as a huge surprise to oddsmakers.
BetOnline.ag was waiting until NFL free agency settled a bit before opening conference lines for 2025 and the Saints and Panthers have the worst odds to win the NFC at 80/1. The defending Super Bowl champion Philadelphia Eagles are the favorites (3/1) followed by the Lions (4/1) and 49ers (15/2);
The Buffalo Bills are the AFC favorites.