Week 12’s slate top two games are from the SEC with Texas heading to Athens to take on Georgia while Oklahoma is at Alabama.
Below are the opening lines for Week 12, courtesy of BetOnline.ag.
College football Week 12 lines are subject to change. Here’s the direct link to real-time spreads: https://www.betonline.ag/sportsbook/football/ncaa.
Week 12 Football Lines
Tuesday, November , 11
- Kent State at Akron (-5)
- Ohio at Western Michigan (+1)
Wednesday, November 12, 2025
- Buffalo at Central Michigan (-1½)
- Northern Illinois at Massachusetts (+11½)
- Toledo at Miami (OH) (+3½)
Thursday, November 13, 2025
- Troy at Old Dominion (-11)
Friday, November 14, 2025
- Clemson at Louisville (-3)
- Minnesota at Oregon (-23½)
Saturday, November 15, 2025
- Wisconsin at Indiana (-29½)
- South Carolina at Texas A&M (-19½)
- Notre Dame at Pittsburgh (+10)
- Michigan at Northwestern (+10)
- Arizona at Cincinnati (-6½)
- Kansas State at Oklahoma State (+20)
- Air Force at UConn (-8)
- UTSA at Charlotte (+17½)
- South Florida at Navy (+10)
- Eastern Michigan at Ball State (+3)
- Arkansas at LSU (-6½)
- Oregon State at Tulsa (+1½)
- West Virginia at Arizona State (-11)
- Marshall at Georgia State (+6½)
- North Texas at UAB (+18)
- UTEP at Missouri State (-4½)
- Colorado State at New Mexico (-14)
- Oklahoma at Alabama (-7)
- UCF at Texas Tech (-23½)
- Virginia at Duke (-6)
- Georgia Tech at Boston College (+15½)
- NC State at Miami (-14½)
- Iowa at USC (-6½)
- Penn State at Michigan State (+6½)
- Maryland at Illinois (-14)
- Middle Tennessee at Western Kentucky (-13½)
- San Jose State at Nevada (+8)
- Appalachian State at James Madison (-20)
- South Alabama at UL Monroe (+3½)
- Texas State at Southern Miss (-6½)
- Memphis at East Carolina (-3)
- Florida Atlantic at Tulane (-15½)
- New Mexico State at Tennessee (-39½)
- North Carolina at Wake Forest (-6)
- Liberty at Florida International (+2½)
- Coastal Carolina at Georgia Southern (-2½)
- Florida at Ole Miss (-13½)
- Utah at Baylor (+8½)
- Purdue at Washington (-17)
- Delaware at Sam Houston (+8½)
- Utah State at UNLV (-4½)
- UCLA at Ohio State (-30½)
- Texas at Georgia (-6½)
- Virginia Tech at Florida State (-12½)
- Mississippi State at Missouri (-6½)
- Kennesaw State at Jacksonville State (+2)
- Louisiana Tech at Washington State (-6½)
- TCU at BYU (-6)
- Boise State at San Diego State (-1½)
- Wyoming at Fresno State (-4½)
