Week 12 odds shift toward Saints in NFC South clash

Week 11 saw a virtuoso Josh Allen performance, the Eagles nail down every tiebreaker imaginable in the NFC and more than likely the end of the Chiefs AFC West dominance.

Onto to week 12 where the Colts look to put a nail in the Chiefs coffin.

NFL Week 12 spreads are subject to change. Here’s the direct link to those odds:https://www.betonline.ag/sportsbook/football/nfl.

NFL Week 12 Lines

Thursday, November 20, 2025

• Buffalo Bills at Houston Texans (+3½)

Sunday, Nov 23, 2025

• Pittsburgh Steelers at Chicago Bears (-3)
  • Note: Lookahead line opened Bears -1½.

• New England Patriots at Cincinnati Bengals (+7)
  • Note: Lookahead line opened Bengals +5.

• New York Giants at Detroit Lions (-11½)

• Minnesota Vikings at Green Bay Packers (-6)

• Seattle Seahawks at Tennessee Titans (+13)

• Indianapolis Colts at Kansas City Chiefs (-3½)
  • Note: Lookahead line opened Chiefs -4½.

• New York Jets at Baltimore Ravens (-14½)

• Cleveland at Las Vegas (-3)
  • Note: Lookahead line opened Raiders -2.

• Jacksonville at Arizona (+2½)
  • Note: Lookahead line opened Cardinals +1½.

• Philadelphia Eagles at Dallas Cowboys (+4½)

• Atlanta Falcons at New Orleans Saints (+2½)
  • Note: Lookahead line opened Saints +3½.

• Tampa Bay Buccaneers at Los Angeles Rams (-6½)

Monday, Nov 17, 2025

• Carolina Panthers at San Francisco 49ers (-6½)