NFL Week 18 Odds: Saints look like NFC South’s best team

Week 17 of the 2025 NFL season saw the NFC South ineptitude in full effect. There is an argument that the Saints are currently the best team in the division.

We also saw Pittsburgh miss DK Metcalf immensely as they couldn’t score a TD in Cleveland with a chance to clinch the division.

Onto week 18, where there are possibly three head-to-head matchups for the division championship. We have Baltimore at Pittsburgh, Carolina at Tampa Bay and maybe Seattle at San Francisco for the division and the first round bye at stake.

Aside from those three games and few others, this is the hardest week for oddsmakers to set lines.

This was the only week that did not have lookahead lines due to so much uncertainty.

NFL Week 18 spreads are subject to change. Here’s the direct link to those odds: https://www.betonline.ag/sportsbook/football/nfl.

NFL Week 18 Lines

Sunday January 4^th, 2026

• New Orleans at Atlanta (-2½)

• New York Jets at Buffalo Bills (-12½)

• Detroit Lions at Chicago Bears (-2)

• Cleveland Browns at Cincinnati Bengals (-7)

• Green Bay Packers at Minnesota Vikings (-6)

• Miami Dolphins at New England Patriots (-9½)

• Dallas Cowboys at New York Giants (+6)

• Washington Commanders at Philadelphia Eagles (-12)

• Baltimore Ravens at Pittsburgh Steelers (+3)

• Carolina Panthers at Tampa Bay Buccaneers (-3)

• Tennessee Titans at Jacksonville Jaguars (-11)

• Indianapolis Colts at Houston Texans (-10)

• Seattle Seahawks at San Francisco 49ers (-1)

• Los Angeles Chargers at Denver Broncos (-7)

• Kansas City Chiefs at Las Vegas Raiders (+6)

• Arizona Cardinals at Los Angeles Rams (-14½)