College Football Week 2 Odds: Ohio State-Texas headlines slate

Week 2 of the college football season brings a pair of heavyweight SEC-Big Ten showdowns—and oddsmakers are expecting plenty of drama. Ohio State heads to Texas with the Longhorns looking for revenge, while Michigan gets its shot at payback against Oklahoma. Elsewhere, LSU is a massive home favorite, Alabama hits the road for SEC play and several ranked contenders are laying huge numbers.

College Football Week 2 lines are subject to change. Here’s the direct link to real-time spreads: https://www.betonline.ag/sportsbook/football/ncaa.

Week 2 College Football Lines

Friday September 11^th, 2026

• Rutgers at Boston College (-3.5)

• Missouri at Kansas (+6.5)

Saturday September 12^th, 2026

• Oregon at Oklahoma State (+22)

• Arizona State at Texas A&M (-15.5)

• Oklahoma at Michigan (+6.5)

• Penn State at Temple (+23.5)

• Washington State at Kansas State (-18.5)

• Old Dominion at Virginia Tech (-18)

• Wake Forest at Purdue (+4)

• South Florida at Army (-3)

• Appalachian State at East Carolina (-10)

• Western Kentucky at Georgia (-38.5)

• Rice at Notre Dame (-44.5)

• Alabama at Kentucky (+10.5)

• Arizona at BYU (-7,5)

• Utah State at Washington (-26.5)

• Mississippi State at Minnesota (pk)

• UCF at Pittsburgh (-7.5)

• California at Syracuse (-1)

• Duke at Illinois (-7)

• Eastern Michigan at Michigan State (-19)

• Maryland at UConn (+13.5)

• UTSA at Texas State (+1)

• UL Monroe at UAB (-10.5)

• UNLV at North Texas (+5.5)

• Delaware at Vanderbilt (-20.5)

• Memphis at Boise State (-8.5)

• Buffalo at Florida International (-9.5)

• Jacksonville State at Ohio (-2)

• Tennessee at Georgia Tech (+13.5)

• Bowling Green at Nebraska (-28.5)

• Tulsa at Sam Houston (+14)

• South Alabama at Tulane (-11.5)

• Louisiana Tech at LSU (-32.5)

• Middle Tennessee at Marshall (-17.5)

• San Diego State at UCLA (-10.5)

• Ohio State at Texas (+1)

• Texas Tech at Oregon State (+27.5)

• Iowa State at Iowa (-14.5)

• Georgia Southern at Clemson (-23.5)

• Navy at Florida Atlantic (-6.5)

• Southern Miss at Auburn (-29.5)

• Charlotte at Ole Miss (-46.5)

• Arkansas at Utah (-10.5)

• Louisiana at USC (-29)

• New Mexico State at Hawai’i (-11.5)

Please note, these lines are not live yet. Please feel free to check in for them later today or tomorrow.

• Georgia State at Kennesaw State

• North Dakota State at Air Force

• Sacramento State at Fresno State